The future of oral care starts now. Let’s formulate it together!

We are specialized in oral care formulation, helping brands create, improve, and scale high‑performance oral care products.

How can we help you?

Formulation

We formulate — or reformulate — oral care products across every major category: toothpaste, mouthwash, gels, enamel strengtheners, whitening systems, and more.
Have an idea for a new product category? We’ve developed entirely new concepts for companies around the world, including microbiome‑aligned formulations that support a healthier oral ecosystem.
Already have a product? We upgrade it with natural ingredients, remineralization strategies, and next‑generation technologies.

Troubleshooting & Upscaling

We solve formulation challenges at any stage — from ingredient replacement to improving stability, texture, and performance.
Need to upscale? We support pilot‑to‑factory transitions, identify suitable private‑label manufacturers, and guide packaging choices that fit your formula and market.
Whether you’re stuck, scaling, or optimizing, we make sure your product works the way it should.

Whitening

Whitening regulations differ by country, and hydrogen peroxide limits can be complex.
We’ve formulated many of today’s effective and legally compliant whitening gels, tailored to regional requirements.
Whether you need to fix an existing product or develop a new whitening system for your market, we ensure safety, compliance, and strong performance.

Creating Your Own Oral Care Brand

From idea to shelf‑ready product — we build your brand with you.

Whether you’re launching your first oral care line or expanding an existing portfolio, we guide you through every step of creating a high‑performance, compliant, and commercially viable brand. We help you define your product architecture, select the right actives, and build formulas that match your positioning — natural, clinical, microbiome‑friendly, whitening‑focused, or premium science‑driven.

Need manufacturing? We connect you with trusted private‑label and contract manufacturers, prepare technical documentation, and ensure your formula is ready for scale. Need differentiation? We design unique concepts, ingredient stories, and performance claims that stand out in a crowded market.

From concept to formulation, from samples to production — we help you create an oral care brand built on real science and real performance.

What kind of oral care brand are you looking to build?

The future of oral care starts now. Let’s formulate it together!

Oral Care Formulation

Nequia develops modern, science‑driven oral care formulations for brands across Europe and the United States. With more than 15 years of hands‑on experience, we help companies create products that are stable, effective, and ready for manufacturing. We combine practical formulation expertise with an innovative, out‑of‑the‑box mindset to help brands move faster and smarter.

Our work is grounded in real‑world production knowledge. We focus on what truly matters: formulations that perform well, scale smoothly, and support your brand’s positioning.

How We Work

Our process is simple, structured, and designed to give you clarity at every step. We begin by understanding your product goals, your target market, and the type of performance you want to deliver. From there, we translate your ideas into a formulation strategy that is realistic, technically sound, and aligned with your brand identity.

We also work efficiently. Instead of long development cycles, we focus on fast, smart iterations. This approach helps you move forward without delays and gives you a clear overview of what is possible within your budget, timeline, and manufacturing capabilities.

In addition to the core development work, we also help you understand the strategic implications of your formulation choices. Small adjustments in surfactants, humectants, or actives can influence cost, stability, sensory experience, and even how your product is positioned in the market. We make these considerations clear and easy to understand, so you can make confident decisions without needing a technical background. This structured approach also helps you compare different formulation directions side by side, giving you a transparent overview of what each option offers. By combining technical depth with clear communication, we ensure that every step of development supports your brand’s long‑term goals.

Remineralisation Technologies

Remineralisation is a core part of many oral care products. We work with the two systems that are most widely used and well‑supported.

Hydroxyapatite

Hydroxyapatite is a biomimetic ingredient that supports enamel and helps reduce sensitivity. It is available in different particle sizes and grades, each with its own performance profile. We help you choose the right type based on:

  • your product format
  • your sensory goals
  • your target market
  • ingredient compatibility

Fluoride

Fluoride remains one of the most effective and well‑researched remineralisation ingredients. We help you integrate it into your formulation in a way that is stable, safe, and aligned with your product positioning.

Active Ingredient Strategy

Active ingredients define the performance of your product. We help you select and integrate the right actives based on your goals, your market, and your formulation architecture.

  • desensitising agents
  • anti‑plaque technologies
  • anti‑malodour ingredients
  • soothing botanical extracts
  • enzyme‑based systems

Whitening Formulations (Peroxide‑Based)

For brands that want a whitening product, we also develop formulations based on carbamide peroxide and hydrogen peroxide. These systems are typically used in:

  • whitening pens
  • whitening gels

How We Evaluate Actives

  • compatibility with surfactants and abrasives
  • pH requirements
  • stability over time
  • sensory impact
  • interaction with flavours
  • expectations in your target markets

Our goal is to help you choose actives that deliver real performance without compromising stability or user experience.

Microbiome‑Aligned Formulation

Modern oral care increasingly focuses on supporting a balanced oral microbiome. We help you develop formulations that are gentle, effective, and aligned with this approach.

Surfactant Strategy

  • are mild
  • support microbiome‑friendly positioning
  • work with your chosen actives
  • deliver the right sensory profile

Microbiome‑Friendly Development

  • ingredient screening
  • pH strategy
  • surfactant optimisation
  • prebiotic and postbiotic options
  • documentation for microbiome‑aligned positioning

The goal is simple: a product that performs well without disrupting the natural balance of the mouth.

Formulation Architecture

  • abrasive systems
  • humectant balance
  • binders and viscosity
  • surfactant blends
  • flavour integration
  • preservative systems

End‑Product Specifications

  • pH
  • viscosity
  • appearance
  • stability expectations
  • performance expectations
  • packaging compatibility (end‑product only)

These specifications ensure your product is ready for manufacturing and quality control.

Full Formulation Package

  • INCI list
  • percentage breakdown
  • phase structure (A/B/C)
  • mixing order
  • equipment notes
  • expected texture and viscosity
  • stability considerations
  • production method (clear, step‑by‑step)

This gives your manufacturer everything they need to produce the product correctly and consistently.

Production Method

  • how to combine the phases
  • the correct mixing order
  • equipment considerations
  • batch instructions
  • scale‑up guidance (lab → pilot → manufacturer)

This ensures a smooth transition from development to production.

Prototype Development

We create prototypes that match your product goals and positioning. Each prototype is designed to be stable, sensory‑balanced, compatible with your packaging, and ready for testing.

Prototype Iterations

  • viscosity
  • flavour
  • foam profile
  • texture
  • colour
  • stability

We test small changes quickly, helping you move forward without delays. Our hands‑on approach ensures that each iteration brings you closer to the final product — without unnecessary complexity.

How We Evaluate Prototypes

  • stability over time
  • user experience
  • flavour performance
  • packaging behaviour
  • compatibility with actives
  • manufacturability

This helps you make informed decisions before moving to scale‑up.

Ingredient Incompatibility Analysis

  • surfactant–active conflicts
  • abrasive–active interactions
  • flavour instability
  • preservative incompatibilities
  • pH‑dependent degradation
  • raw material variability

This prevents problems before they appear in production.

Filling Whitening Pens

We also support peroxide‑based whitening products during scale‑up, including viscosity control, stabiliser selection, and packaging compatibility for both pens and tubes.

Finding the Right Private‑Label Manufacturer

  • find the right manufacturer for your product
  • match your formulation to their capabilities
  • prepare the documentation they need
  • support the first production run
  • solve issues during pilot batches

How We Select Manufacturers

  • product category expertise
  • equipment capabilities
  • batch size options
  • quality standards
  • communication style
  • flexibility for smaller brands

This saves time, reduces risk, and ensures a smoother path to market.

Supporting Teams With Limited Formulation Capacity

Many of our clients do not have a full R&D department. Some have only a small technical team; others are marketing‑driven and rely entirely on external expertise. We are used to working in that environment.

  • taking ownership of the formulation work
  • preparing clear documentation for internal stakeholders
  • joining technical discussions with manufacturers
  • helping you evaluate samples and test results

This allows you to offer high‑quality oral care products without building a large internal formulation team.

Oral Care Formulator Program

The Oral Care Formulator Program is an internal tool we use to support the development process. It is a custom HTML‑based system that allows us to build formulations quickly, explore different ingredient combinations, and structure a complete formula in a clear, consistent way.

The tool helps us select and balance key components such as humectants, abrasives, surfactants, binders, actives, flavours, and preservatives. As we build the formulation, the program provides high‑level indication signals for both EU and US (FDA‑related) contexts. These indications do not replace regulatory review, but they help us identify areas that may require additional attention early in the process.

How It Supports Your Project

  • create structured formulation drafts more efficiently
  • explore multiple formulation directions quickly
  • identify potential incompatibilities or regulatory considerations early
  • present clear, well‑organised formulation options to you
  • ensure consistency across prototypes and documentation

By using this tool internally, we can move faster, reduce development uncertainty, and give you a more transparent view of how your formulation is built.

Why Brands Work With Nequia

  • 15+ years of specialised oral care formulation experience
  • Strong network of trusted manufacturers
  • Clear, minimalistic communication
  • Practical solutions that work in real production environments
  • Deep understanding of modern oral care trends
  • Support from concept to scale‑up
  • Hands‑on, innovative, out‑of‑the‑box thinking

Our focus is always on building formulations that are technically strong, commercially relevant, and aligned with your brand’s direction.

Let’s explore your next formulation step

From early‑stage concepts to production‑ready formulas, we support your development process with clarity, speed, and scientific depth.